Oxandrolone was established in 1964 in the depths of the American company “Searle» (Searle Co) and sold under the trademark “Anavar” in the US market more than 25 years. The creators of the steroid can rightly be regarded as the two employees, “Searle” – Young and Pappo, they developed the idea of introduction of hetero atoms in the steroid skeleton. After a series of not very successful attempts oxygen was introduced into the second position (ring A), which gave a result of the drug, later called oxandrolone. The first experiments on rats have shown a sharp decline in experimental animals the nitrogen in the urine, which is an indication of increasing protein synthesis muscle fibers, but at the same time, the almost complete lack of tangible growth in both muscles (remember, in this kind of experiment is considered a muscle levator ani), and prostate. July 1, 1989 the production of Anavar was phased out of the US, but its analogues continue to be issued until now. In recognition of the famous bodybuilder Krischena Mike (Mike Christian), it Anavar was his first anabolic steroids and achieved impressive increases of in strength and mass. History is silent about the dosage used by the Mr. Krischen, but he still remains almost the only athlete who is able to. Application Unlike the vast majority of anabolic steroids, the main use of oxandrolone lies beyond sport – this drug is very widely used in medical practice. As for sports, there oxandrolone is used mainly in track and field, swimming etc. In power sports – bodybuilding, powerlifting, barbell, strongman – where it is used as a rarely. The main obstacle to its use sportsmenami- “siloviki” – a very high price (if the same athletes may cost 2-4 oxandrolone tablets a day, the “siloviki” required dose several times higher, about dosages see. Below). With the ability to greatly enhance the synthesis of creatine phosphate muscle fibers, oxandrolone may provide a significant increase in power, without leading to a significant increase in weight – a quality that can be appreciated by athletes lighter weight categories. That gain in terms of power – the main advantage of oxandrolone as regards the set weight, it is hardly justified to use for this purpose is so expensive means. Despite the fact that very good oxandrolone stabilizes the androgen receptor (perhaps even better than testosterone), its application even at very high doses does not lead to a significant increase in muscle mass. At the same time oxandrolone is perhaps the most powerful anti-catabolic, it very well “occupied” cortisol receptors, as their antagonist (prevents activation). For this reason oxandrolone is often used in between cycles to maintain gain muscle mass (here it is usually combined with Andriol – testosterone undecanoate), and in preparation for a competition, if the use of testosterone propionate is undesirable. By the way, in addition to the anti-catabolic...
Read MoreAnavar – Side Effects
